Want to stay young and avoid problems like cataracts,
Just minimize the sugar in your diet.Sugar, it turns out, has a not so sweet side to it. It takes you on a fast ride over the hill.
Sugar circulating in the
Simply put, AGEs age you.
How Advanced Glycation End Products (AGEs) Age You Fast!
These molecules leave a path of destruction throughout your body. AGEs are responsible for the nerve death, tissue damage and eye problems associated with diabetes. And they play a big role in the stiffening of the arteries associated with heart disease.
How does this happen?
AGEs do three different things to age your body fast:
1. They cross-link with proteins, stiffening affected tissues.
2. They increase oxidative stress also known as free radical damage.
3. They trigger inflammation through a number of pathways.
4. While AGEs are found throughout the body, tissues that go through less cellular renewal over time are the most vulnerable to AGE damage. This includes the tissue in your arteries and heart, the lens of the eye, muscle tissue,
By cross-linking with proteins like collagen, AGEs turns tissue from being pliant and healthy into wiry, scarred wrecks inside your body. Arteriosclerosis is an example of this.
But this is only the beginning of the problems AGEs cause . . .
Because along with AGE come RAGE!
Some tissues - like the muscles,
People with heart disease and type 2 diabetes have particularly high levels of these special RAGE receptors. [3]
How AGEs Get In Your Body
High blood sugar is one way AGEs get a foothold in your body. So diabetics are particularly vulnerable to these monster molecules. [4] But even just eating a lot of sugar, leading to blood sugar levels spikes can cause AGE accumulation.
Not only does your body make AGEs, you can also get AGEs when you eat AGE-rich foods.
Grilled, roasted and fried meats are one of the main sources of dietary AGEs. That rich flavor created by browning meats is really a sign that you've created AGEs as the sugars and amino acids in meat bind together. [5]
Many processed foods are also high in AGEs. Baked or fried pastries with a browned crust . . . breakfast cereals . . . even pasteurized milk can contain AGEs. [6]
Keep AGEs Out Of Your Body And Slow Aging Down
How can you keep AGEs inside you down to a minimum?
1. Cut down on sugar. The less sugar you eat, the less sugar in circulation inside of you. And the
2. Cut down on AGE-rich foods. Instead of baking, roasting, frying or grilling try cooking without dry heat.
3. Cook stews instead of roasts. And eat grains cooked in water like rice and oatmeal instead of bread and crackers.
4. If you have diabetes, pay keen attention to your blood sugar levels. Using diet and other interventions, you can make a tremendous difference in the AGE damage your body incurs.
5. Antioxidant-rich foods like red grape juice extract have been shown to reduce the formation of AGEs due to their antioxidant activity.
6. [7]Exercise. A number of studies have shown exercising can help you eliminate the buildup of AGEs throughout your body.[8]
While we can't stop time, we have tremendous control over how we age. You can minimize the accumulation of AGEs inside of your body. And by stopping AGEs, you can help slow the aging process in your body.
About Dr. Mark Drucker, M.D.
Dr. Mark Drucker earned his Medical degree and Bachelor of Sciences degree
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Sources:
[1] Semba R et al. Does Accumulation of Advanced Glycation End Products Contribute to the Aging Phenotype? J Gerontol A Biol Sci Med Sci. Sep 2010; 65A(9): 963-975.
[2] Semba et al.
[3] Radoi V et al. Advanced glycation end products in diabetes mellitus: mechanism of action and focused treatment. Proc. Rom. Acad., Series B, 2012, 1, p. 9-19 [4] Sugimoto K, Yasujima M, Yagihashi S, Role of advanced glycation end products in diabetic neuropathy. CurrPharm Des. 2008; 14(10):953-61.